Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMSJGQE)

Drug Name

3-(3-Carboxy-propionylamino)-benzoic acid Drug Info

Synonyms

CHEMBL296834; 3-(3-carboxypropanamido)benzoic acid; 3-[(3-carboxypropanoyl)amino]benzoic acid; 259222-20-3; IFLab1_001254; 3-(3-carboxypropanoylamino)benzoic acid; 3-(3-Carboxy-propionylamino)-benzoic acid; AC1LFPO3; Oprea1_683242; Oprea1_208346; CTK0J3689; DTXSID30353899; MolPort-000-385-127; HMS1415I22; ZINC216961; STK032065; BDBM50127981; AKOS000112854; MCULE-6483245282; IDI1_009121; ST50036495; 3-(4-Oxo-4-hydroxybutyrylamino)benzoic acid; 3-[(4-hydroxy-4-oxobutanoyl)amino]benzoic acid; SR-01000005669; Benzoic acid, 3-[(3-carbo

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 757562
CAS Number: CAS 259222-20-3
TTD Drug ID: DMSJGQE

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Acetylcholinesterase (AChE)	TT1RS9F	ACES_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Acetylcholinesterase (AChE)	DTT	ACHE	1.678	1.926	1.766	5.252

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Acetylcholinesterase (AChE)	DTT	ACHE	6.39E-02	-1.07	-1.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthesis, anticholinesterase activity and structure-activity relationships of m-Aminobenzoic acid derivatives. Bioorg Med Chem Lett. 2003 May 19;13(10):1825-7.