Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMV4I0K)

Drug Name
Cyclopropylamine derivative 12 Drug Info
Synonyms PMID27019002-Compound-33d
Cross-matching ID
TTD Drug ID
DMV4I0K

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Lysine-specific histone demethylase 1 (LSD) TTNR0UQ KDM1A_HUMAN Inhibitor [1]
Monoamine oxidase (MAO) TT32XQJ NOUNIPROTAC Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Lysine-specific histone demethylase 1 (LSD) DTT KDM1A 4.973 7.144 6.517 4.597
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Lysine-specific histone demethylase 1 (LSD) DTT KDM1A 1.51E-76 0.51 1.91
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 LSD1 inhibitors: a patent review (2010-2015).Expert Opin Ther Pat. 2016 May;26(5):565-80.