Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TT32XQJ)

DTT Name Monoamine oxidase (MAO)
Synonyms Human monoamine oxidase
Gene Name NO-GeName
DTT Type
Successful target
 [1]
Related Disease
Acquired methaemoglobinaemia [ICD-11: 3A93]
Alzheimer disease [ICD-11: 8A20]
Depression [ICD-11: 6A70-6A7Z]
Hypertension [ICD-11: BA00-BA04]
Parkinsonism [ICD-11: 8A00]
UniProt ID
NOUNIPROTAC
TTD ID
T62151

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
8 Approved Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [2]
Ergoloid mesylate DMORPBA Alzheimer disease 8A20 Approved [1]
Methylene blue DMJAPE7 Acquired methemoglobinemia 3A93 Approved [3]
Moclobemide DMNZWL7 Depression 6A70-6A7Z Approved [2]
Pargyline DMM0HR1 Hypertension BA00-BA04 Approved [2]
Phenelzine DMHIDUE Depression 6A70-6A7Z Approved [2]
Selegiline DM6034S Major depressive disorder 6A70.3 Approved [2]
Tranylcypromine DMGB5RE Major depressive disorder 6A70.3 Approved [2]
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10 Patented Agent(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
(-)-deprenyl DMMLQAS Alopecia ED70 Patented [2]
Cyclopropylamine derivative 10 DMZ5WN8 N. A. N. A. Patented [4]
Cyclopropylamine derivative 11 DMMJ0YN N. A. N. A. Patented [4]
Cyclopropylamine derivative 12 DMV4I0K N. A. N. A. Patented [4]
Cyclopropylamine derivative 13 DMXNVD4 N. A. N. A. Patented [4]
Cyclopropylamine derivative 9 DMX7YAL N. A. N. A. Patented [4]
Lazabemide DMCULK7 Skin imperfections EK71 Patented [2]
N-(2-phenylcyclopropyl) amino acid derivative 2 DM6YV3O N. A. N. A. Patented [4]
PMID27019002-Compound-17 DM7JASU N. A. N. A. Patented [4]
PMID27019002-Compound-20a DMRX748 N. A. N. A. Patented [4]
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⏷ Show the Full List of 10 Patented Agent(s)

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
2 Novel monoamine oxidase inhibitors: a patent review (2012 - 2014).Expert Opin Ther Pat. 2015 Jan;25(1):91-110.
3 Photoluminescence of CdTe nanocrystals modulated by methylene blue and DNA. A label-free luminescent signaling nanohybrid platform. Phys Chem Chem Phys. 2009 Jul 7;11(25):5062-9.
4 LSD1 inhibitors: a patent review (2010-2015).Expert Opin Ther Pat. 2016 May;26(5):565-80.