Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM1T2LS)

Drug Name

Salicin Drug Info

Synonyms

salicin; 138-52-3; Salicoside; Salicine; Salicyl alcohol glucoside; D-(-)-Salicin; (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(2-(hydroxymethyl)phenoxy)tetrahydro-2H-pyran-3,4,5-triol; 2-(Hydroxymethyl)phenyl beta-D-glucopyranoside; Saligenin beta-D-glucopyranoside; D-Salicin; Saligenin-beta-D-glucopyranoside; 2-(Hydroxymethyl)phenyl-beta-d-glucopyranoside; Salicin (6CI,8CI); D(-)-Salicin; o-(Hydroxymethyl)phenyl beta-D-glucopyranoside; Benzyl alcohol, o-hydroxy-, o-glucoside; UNII-4649620TBZ; AI3-19099; alpha-Hydroxy-o-tolyl beta

Indication

Disease Entry	ICD 11	Status	REF
Analgesia	MB40.8	Approved	[1]

Cross-matching ID

PubChem CID: 439503
ChEBI ID: CHEBI:17814
CAS Number: CAS 138-52-3
TTD Drug ID: DM1T2LS
INTEDE Drug ID: DR2482

Molecule-Related Drug Atlas

Molecule Type:

DME

DOT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Affected By Taste receptor type 2 member 16 (TAS2R16)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[4]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Phospho-beta-glucosidase (LBA1706)^{Main DME}	DEFKVZD	Q5FIF6_LACAC	Substrate	[2]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Taste receptor type 2 member 16 (TAS2R16)	OT67HLNS	T2R16_HUMAN	Gene/Protein Processing	[3]

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References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	Microbial unmasking of plant glycosides. mBio. 2018 Jan 30;9(1). pii: e02433-17.
3	Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin. PLoS One. 2011;6(5):e20123.
4	Integrative omics data analyses of repeated dose toxicity of valproic acid in vitro reveal new mechanisms of steatosis induction. Toxicology. 2018 Jan 15;393:160-170.
5	Air pollution and DNA methylation alterations in lung cancer: A systematic and comparative study. Oncotarget. 2017 Jan 3;8(1):1369-1391. doi: 10.18632/oncotarget.13622.