Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM1W7LV)

Drug Name

CAR-T cells targeting MAGE-A1 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Lung cancer	2C25.0	Phase 1/2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Discontinued Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Melanoma-associated antigen 1 (MAGEA1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Melanoma vaccine (ALVAC)	DM3HIQY	Melanoma	2C30	Discontinued in Phase 2	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Melanoma-associated antigen 1 (MAGEA1)	TT63M7Q	MAGA1_HUMAN	CAR-T-Cell-Therapy	[1]

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References

1	ClinicalTrials.gov (NCT03356808) Antigen-specific T Cells Against Lung Cancer
2	Preclinical qualification of a new multi-antigen candidate vaccine for metastatic melanoma. J Immunother. 2010 Oct;33(8):743-58.