Details of the Drug

General Information of Drug (ID: DM1W7LV)

Drug Name
CAR-T cells targeting MAGE-A1
Indication
Disease Entry ICD 11 Status REF
Lung cancer 2C25.0 Phase 1/2 [1]
Drug Type
CAR T Cell Therapy
Cross-matching ID
TTD ID
D0NA4J

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Melanoma-associated antigen 1 (MAGEA1) TT63M7Q MAGA1_HUMAN CAR-T-Cell-Therapy [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Lung cancer
ICD Disease Classification 2C25.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Melanoma-associated antigen 1 (MAGEA1) DTT MAGEA1 6.96E-12 0.59 1.39
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03356808) Antigen-specific T Cells Against Lung Cancer