General Information of Drug (ID: DM31QEY)

Drug Name
PMID32321856-compound-11b Drug Info
Synonyms PMID32321856-C-11b
Indication
Disease Entry ICD 11 Status REF
Coronavirus Disease 2019 (COVID-19) 1D6Y Investigative [1]
Therapeutic Class
Antiviral Agents
Cross-matching ID
TTD Drug ID
DM31QEY

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Preclinical Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [2]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [3]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [2]
PX-12 DMLVHAJ Pancreatic cancer 2C10 Phase 2 [2]
Tideglusib DME4LA1 Alzheimer disease 8A20 Phase 2 [2]
Hexylcarbamoyl fluorouracil DMYNPK8 Solid tumour/cancer 2A00-2F9Z Withdrawn from market [2]
PMID26868298-compound-N3 DMQFUCD Middle East Respiratory Syndrome (MERS) 1D64 Preclinical [2]
GRL0617 DMX9AGF Coronavirus infection 1D92 Preclinical [4]
Isoarnebin 4 DM0B7NO Coronavirus Disease 2019 (COVID-19) 1D6Y Investigative [2]
PMID32321856-compound-11a DMN39V6 Coronavirus Disease 2019 (COVID-19) 1D6Y Investigative [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
COVID-19 papain-like proteinase (PL-PRO) TTNHMO8 R1AB_SARS2 (819-2763) Inhibitor [1]

References

1 Structure-based Design of Antiviral Drug Candidates Targeting the SARS-CoV-2 Main Protease. Science. 2020 Apr 22;eabb4489.
2 Structure of Mpro from COVID-19 virus and discovery of its inhibitors. Nature. 2020 Apr 9.
3 ClinicalTrials.gov (NCT04361422) Isotretinoin in Treatment of COVID-19. U.S. National Institutes of Health.
4 Crystal structure of SARS-CoV-2 papain-like protease. Acta Pharm Sin B. 2021 Jan;11(1):237-245.