General Information of Drug (ID: DM5C7I8)

Drug Name
1-(3,4-dihydronaphthalen-1-yl)ethanone Drug Info
Synonyms
CHEMBL378621; 1-(3,4-dihydro-naphthalen-1-yl)-ethanone; 67106-36-9; 1-(3,4-dihydronaphthalen-1-yl)ethanone; SCHEMBL6337844; 1-acetyl-3,4-dihydronaphthalene; CTK1J3902; DTXSID40447596; BDBM50189272; AKOS030597011; 1-(3,4-dihydro-1-naphthalenyl)ethanone; Ethanone, 1-(3,4-dihydro-1-naphthalenyl)-
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
10899142
TTD Drug ID
DM5C7I8

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
TRICLABENDAZOLE DMPWGBR Helminth infection 1F90.0 Approved [2]
MANIDIPINE DMJPGUA N. A. N. A. Phase 3 [2]
L-755507 DMPWBNU N. A. N. A. Terminated [3]
GNF-PF-4478 DMCDU8K Discovery agent N.A. Investigative [4]
K-777 DMIFCMW Discovery agent N.A. Investigative [5]
WRR-99 DM8ZA6K Discovery agent N.A. Investigative [6]
Benzoyl-Arginine-Alanine-Methyl Ketone DMC7TNF Discovery agent N.A. Investigative [6]
Vinylsulphones DMNFVO7 Infection of P. falciparum 1F40 Investigative [7]
WRR-112 DMP761U Discovery agent N.A. Investigative [6]
1-(3-Methoxy-benzyl)-5-methyl-1H-indole-2,3-dione DM30M9H Discovery agent N.A. Investigative [8]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Trypanosoma Cruzipain (Trypano CYSP) TTEAID7 CYSP_TRYCR Inhibitor [1]

References

1 Design, synthesis, and biochemical evaluation of novel cruzain inhibitors with potential application in the treatment of Chagas' disease. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4405-9.
2 Colloid formation by drugs in simulated intestinal fluid. J Med Chem. 2010 May 27;53(10):4259-65.
3 Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease. J Med Chem. 2010 Jan 14;53(1):37-51.
4 Complementarity between a docking and a high-throughput screen in discovering new cruzain inhibitors. J Med Chem. 2010 Jul 8;53(13):4891-905.
5 Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6218-21.
6 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
7 Opportunities and challenges in antiparasitic drug discovery. Nat Rev Drug Discov. 2005 Sep;4(9):727-40.
8 Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3527-30.