Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM5NLQE)

Drug Name
2-(2-phenethylphenyl)isoindoline-1,3-dione Drug Info
Synonyms CHEMBL246144; PP2P; SCHEMBL2464969; BDBM23840; N-(2-Phenethylphenyl)phthalimide
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
10616182
TTD Drug ID
DM5NLQE

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Oxysterols receptor LXR-alpha (NR1H3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
US9073931, E2 DMK9FJG N. A. N. A. Patented [2]
BDBM50177019 DMEL28G N. A. N. A. Patented [3]
US9006244, E2b DMP0TBO N. A. N. A. Patented [4]
US9073931, E1 DM2Z43I N. A. N. A. Patented [2]
US9006244, E1 DMBF1C0 N. A. N. A. Patented [4]
BDBM50177012 DM52IQF N. A. N. A. Patented [3]
US9006244, E2a DMPDF9B N. A. N. A. Patented [4]
67S DMJL1MB N. A. N. A. Patented [3]
US9073931, E3 DMCYM8P N. A. N. A. Patented [2]
desmosterol DMV8SUM Discovery agent N.A. Investigative [5]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Oxysterols receptor LXR-alpha (NR1H3) TTECBXN NR1H3_HUMAN Inhibitor [1]

References

1 Separation of alpha-glucosidase-inhibitory and liver X receptor-antagonistic activities of phenethylphenyl phthalimide analogs and generation of LX... Bioorg Med Chem. 2009 Jul 15;17(14):5001-14.
2 Liver X receptor modulators. US9073931.
3 Piperazine derivatives as liver X receptor modulators. US10144715.
4 Liver X receptor modulators. US9006244.
5 Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands. J Biol Chem. 2006 Sep 22;281(38):27816-26.