General Information of Drug (ID: DM90WJH)

Drug Name
Interferon alfacon-1 Drug Info
Synonyms Advaferon; Infergen; Advaferon (TN); Infergen (TN); Interferon alfacon-1 (genetical recombination); Interferon alfacon-1 (USAN/INN); Interferon alfacon-1 (genetical recombination) (JAN)
Indication
Disease Entry ICD 11 Status REF
Hepatitis C 1E51 Approved [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
TTD Drug ID
DM90WJH

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Interferon alfa-n1 DM4AK0Q Chronic myelogenous leukaemia 2A20.0 Approved [3]
Interferon Alfa-2b, Recombinant DM3TPY8 Hairy cell leukaemia 2A82.2 Approved [4]
Sifalimumab DM1BS03 Renal cell carcinoma 2C90 Approved [5]
Interferon beta-1b DMCN61Z Multiple sclerosis 8A40 Approved [6]
Anifrolumab DM3FPAQ Systemic lupus erythematosus 4A40.0 Approved [7]
Alfa-interferon DMXMK5S Endometriosis GA10 Phase 1 [8]
⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interferon alpha/beta receptor 2 (IFNAR2) TTMQB37 INAR2_HUMAN Binder [2]

References

1 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
2 Retreating chronic hepatitis C with daily interferon alfacon-1/ribavirin after nonresponse to pegylated interferon/ribavirin: DIRECT results. Hepatology. 2009 Jun;49(6):1838-46.
3 Lymphoblastoid interferon alfa-n1 improves the long-term response to a 6-month course of treatment in chronic hepatitis C compared with recombinant interferon alfa-2b: results of an international randomized controlled trial. Clinical Advisory Group for the Hepatitis C Comparative Study. Hepatology. 1998 Apr;27(4):1121-7.
4 Successful treatment of relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia with T315I mutation after haplo-identical hematopoie... Leuk Res. 2009 Aug;33(8):e111-3.
5 Clinical pipeline report, company report or official report of AstraZeneca (2009).
6 Interferon-beta(1b) Treatment in Neuromyelitis Optica. Eur Neurol. 2009 Jul 7;62(3):167-170.
7 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
8 New drugs in development for the treatment of endometriosis. Expert Opin Investig Drugs. 2008 Aug;17(8):1187-202.