General Information of Drug (ID: DMBRN2G)

Drug Name
DA-697b Drug Info
Synonyms DZ-697b; Oral anticoagulants, Daiichi
Indication
Disease Entry ICD 11 Status REF
Thrombosis DB61-GB90 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMBRN2G

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug(s) Targeting von Willebrand factor (VWF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Vonvendi DMI783H Von willebrand disease 3B12 Approved [2]
Caplacizumab DMPUKA7 Thrombotic thrombocytopenic purpura 3B64.14 Approved [3]
Recombinant von Willebrand factor/recombinant Factor VIII complex DM7JFDO Von willebrand disease 3B12 Phase 3 [4]
ALX-0081 DM7EBH9 Thrombotic thrombocytopenic purpura 3B64.14 Phase 3 [5]
ARC1779 DM7PCLY Intracranial embolism 8B22.1 Phase 2 [6]
BT-200 DM1EYOF Von willebrand disease 3B12 Phase 2 [7]
DTRI-031 DM0BCT7 Ischemic stroke 8B11.5Z Phase 1 [8]
Mitoflaxone DMO06JV Solid tumour/cancer 2A00-2F9Z Terminated [9]
Auryntricarboxylic acid (ATA) DMOIQ4K Discovery agent N.A. Investigative [9]
⏷ Show the Full List of 9 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
von Willebrand factor (VWF) TT3SZBT VWF_HUMAN Inhibitor [1]

References

1 A new oral antiplatelet agent with potent antithrombotic properties: comparison of DZ-697b with clopidogrel a randomised phase I study. Thromb Haemost. 2010 Jan;103(1):205-12.
2 Clinical pipeline report, company report or official report of Vonvendi.
3 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2019
4 6 Factor VIII Concentrates, Factor VIII/von Willebrand Factor Concentrates, Factor IX Concentrates, Activated Prothrombin Complex Concentrates. Transfus Med Hemother. 2009 December; 36(6): 409-418.
5 Clinical pipeline report, company report or official report of Ablynx
6 Short-Acting Anti-VWF (von Willebrand Factor) Aptamer Improves the Recovery, Survival, and Hemostatic Functions of Refrigerated Platelets. Arterioscler Thromb Vasc Biol. 2019 Oct;39(10):2028-2037.
7 Clinical pipeline report, company report or official report of Guardian Theapeutics
8 Clinical pipeline report, company report or official report of Basking Biosciences
9 Novel approaches to the treatment of thrombosis. Trends Pharmacol Sci. 2002 Jan;23(1):25-32.