Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMC82XN)

Drug Name

ASN04421891 Drug Info

Synonyms

ASN 04421891; ASN-04421891

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting Uracil nucleotide/cysteinyl leukotriene receptor (GPR17)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
LTE4	DMCPB0Q	Discovery agent	N.A.	Investigative	[3]
UDP-glucose	DMLT4JA	Discovery agent	N.A.	Investigative	[4]
LTC4	DM702WR	Discovery agent	N.A.	Investigative	[4]
LTD4	DMIUZX3	Discovery agent	N.A.	Investigative	[4]
ASN04450772	DMKR69T	Discovery agent	N.A.	Investigative	[2]
ASN06917370	DMA20JP	Discovery agent	N.A.	Investigative	[2]
ASN02563583	DMEO3Y4	Discovery agent	N.A.	Investigative	[2]
ASN04885796	DMQ0VZ8	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Uracil nucleotide/cysteinyl leukotriene receptor (GPR17)	TTMPART	GPR17_HUMAN	Agonist	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5518).
2	In silico identification of new ligands for GPR17: a promising therapeutic target for neurodegenerative diseases. J Comput Aided Mol Des. 2011 Aug;25(8):743-52.
3	The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair. PLoS One. 2008;3(10):e3579.
4	The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor. EMBO J. 2006 Oct 4;25(19):4615-27.