Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMCN61Z)

Drug Name
Interferon beta-1b Drug Info
Synonyms Betaferon (TN); Betaseron (TN)
Indication
Disease Entry ICD 11 Status REF
Multiple sclerosis 8A40 Approved [1]
Therapeutic Class
Immunomodulatory Agents
Cross-matching ID
TTD Drug ID
DMCN61Z

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Interferon alpha/beta receptor 2 (IFNAR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Interferon alfa-n1 DM4AK0Q Chronic myelogenous leukaemia 2A20.0 Approved [3]
Interferon Alfa-2b, Recombinant DM3TPY8 Hairy cell leukaemia 2A82.2 Approved [4]
Sifalimumab DM1BS03 Renal cell carcinoma 2C90 Approved [5]
Anifrolumab DM3FPAQ Systemic lupus erythematosus 4A40.0 Approved [6]
Interferon alfacon-1 DM90WJH Hepatitis C 1E51 Approved [7]
Alfa-interferon DMXMK5S Endometriosis GA10 Phase 1 [8]
⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interferon alpha/beta receptor 2 (IFNAR2) TTMQB37 INAR2_HUMAN Binder [2]

References

1 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
2 Interferon-beta(1b) Treatment in Neuromyelitis Optica. Eur Neurol. 2009 Jul 7;62(3):167-170.
3 Lymphoblastoid interferon alfa-n1 improves the long-term response to a 6-month course of treatment in chronic hepatitis C compared with recombinant interferon alfa-2b: results of an international randomized controlled trial. Clinical Advisory Group for the Hepatitis C Comparative Study. Hepatology. 1998 Apr;27(4):1121-7.
4 Successful treatment of relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia with T315I mutation after haplo-identical hematopoie... Leuk Res. 2009 Aug;33(8):e111-3.
5 Clinical pipeline report, company report or official report of AstraZeneca (2009).
6 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
7 Retreating chronic hepatitis C with daily interferon alfacon-1/ribavirin after nonresponse to pegylated interferon/ribavirin: DIRECT results. Hepatology. 2009 Jun;49(6):1838-46.
8 New drugs in development for the treatment of endometriosis. Expert Opin Investig Drugs. 2008 Aug;17(8):1187-202.