Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMDYZRS)

Drug Name

BPS-804 Drug Info

Synonyms

Anti-sclerostin antibody (osteoporosis/hypophophatasia), Novartis

Indication

Disease Entry	ICD 11	Status	REF
Metabolic bone disease	FB8Y	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Sclerostin (SOST)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Romosozumab	DMFJZN0	Postmenopausal osteoporosis	FB83.11	Approved	[3]
UX143	DM89NIB	Osteogenesis imperfecta	LD24.K0	Phase 3	[4]
LY2541546	DMTVU2Q	Osteoporosis	FB83.0	Phase 2	[5]
AMG 167	DMUETI2	Osteoporosis	FB83.0	Phase 1	[6]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT01806610) Study of Safety and Tolerability of BPS804 in Patients With Late-stage Chronic Kidney Disease. U.S. National Institutes of Health.
2	WO patent application no. 2010,1001,79, Self-forming gel system for sustained drug delivery.
3	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2019
4	Clinical pipeline report, company report or official report of Ultragenyx Pharmaceutical
5	Rat-specific decreases in platelet count caused by a humanized monoclonal antibody against sclerostin. Toxicol Sci. 2012 Feb;125(2):586-94.
6	Osteoporosis - a current view of pharmacological prevention and treatment. Drug Des Devel Ther. 2013; 7: 435-448.