Details of the Drug-Related molecule(s) Interaction Atlas

US8921389, 210 Drug Info

SCHEMBL12502343; CHEMBL3639757; VSKYLKKDQYXUIH-UHFFFAOYSA-N; BDBM141750; US8921389, 210; 3-{[1-Benzyl-5-hydroxy-2-oxo-3-(2-trifluoromethyl-phenyl)-1,2-dihydro-[1,7]naphthyridine-6-carbonyl]-amino}-propionic acid

Cross-matching ID

PubChem CID

60152500

TTD Drug ID

DME1A80

General Information of Drug (ID: DME1A80)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

Download the Complete Related Drug List

Drug(s) Targeting HIF-prolyl hydroxylase 2 (HPH-2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
FG-4592	DM4XSQ2	Anaemia	3A90	Phase 3	[2]
US9422240, 1-298	DMH7DL5	N. A.	N. A.	Patented	[3]
US8598210, Table XV, 2	DMDK98P	N. A.	N. A.	Patented	[4]
US8536181, A41	DMF9LNO	N. A.	N. A.	Patented	[5]
US8598210, Table XV, 5	DMEU5ST	N. A.	N. A.	Patented	[6]
US8536181, C17	DMRTL63	N. A.	N. A.	Patented	[7]
US8598210, Table XV, 4	DM3XWMO	N. A.	N. A.	Patented	[8]
US8536181, C35	DMAM51Z	N. A.	N. A.	Patented	[5]
US10100051, Compound 2	DMWESZ1	N. A.	N. A.	Patented	[9]
US8921389, 2	DMX7KDR	N. A.	N. A.	Patented	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Naphthyridine derivatives as inhibitors of Hypoxia inducible factor (HIF) hydroxylase. US9695170.
2	Crystalline forms of a prolyl hydroxylase inhibitor. US9115085.
3	Partially saturated nitrogen-containing heterocyclic compound. US9422240.
4	Prolyl hydroxylase inhibitors and methods of use. US9598370.
5	Prolyl hydroxylase inhibitors. US8536181.
6	Prolyl hydroxylase inhibitors and method of use. US8722895.
7	Methods for increasing the stabilization of hypoxia inducible factor-1 alpha. US8778412.
8	Prolyl hydroxylase inhibitors and methods of use. US8598210.
9	Compound of 5-hydroxyl-1,7-naphthyridine substituted by aryloxy or heteroaryloxy, preparation method thereof and pharmaceutical use thereof. US10100051.