Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DME4US7)

Drug Name
GSK3858279 Drug Info
Indication
Disease Entry ICD 11 Status REF
Osteoarthritis pain MG30.31 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DME4US7

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
C-C motif chemokine 17 (CCL17) TTMPHAE CCL17_HUMAN Not Available [2]

References

1 ClinicalTrials.gov (NCT05838755) A Multicenter Randomized, Double-blind, Placebo-controlled Phase 2 Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Target Engagement of GSK3858279 in Adult Participants With Chronic Diabetic Peripheral Neuropathic Pain (DPNP) /NEPTUNE-17. U.S.National Institutes of Health.
2 Therapeutic options for targeting inflammatory osteoarthritis pain. Nat Rev Rheumatol. 2019 Jun;15(6):355-363.