Details of the Drug

General Information of Drug (ID: DME4US7)

Drug Name
GSK3858279
Indication
Disease Entry ICD 11 Status REF
Osteoarthritis pain MG30.31 Phase 2 [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
D21SVO

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
C-C motif chemokine 17 (CCL17) TTMPHAE CCL17_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT05838755) A Multicenter Randomized, Double-blind, Placebo-controlled Phase 2 Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Target Engagement of GSK3858279 in Adult Participants With Chronic Diabetic Peripheral Neuropathic Pain (DPNP) /NEPTUNE-17. U.S.National Institutes of Health.
2 Therapeutic options for targeting inflammatory osteoarthritis pain. Nat Rev Rheumatol. 2019 Jun;15(6):355-363.