Details of the Drug-Related molecule(s) Interaction Atlas

Pyrene-1-aldehyde Drug Info

Pyrene-1-carbaldehyde; RCYFOPUXRMOLQM-UHFFFAOYSA-N; 1-Formylpyrene; KSC224M2B; PYRENECARBOXALDEHYDE; pyrene carboxaldehyde; pyrene-1-carboxaldehyde; pyrenecarbaldehyde; 1-PYRENECARBOXALDEHYDE; 1-Pyrene carboxaldehyde; 1-Pyrene-carboxaldehyde; 1-Pyrenealdehyde; 1-Pyrenecarbaldehyde; 3-Formylpyrene; 3-Pyrenealdehyde; 3-Pyrenecarboxaldehyde; 3-Pyrenylaldehyde; 3029-19-4; AC1L5OS9; AC1Q6PUX; AC1Q6QH9; ACMC-209hea; CCRIS 3163; EINECS 221-196-6; I9H95PVI1P; MFCD00004139; NSC 30811; SCHEMBL52121; UNII-I9H95PVI1P

Cross-matching ID

PubChem CID

232848

CAS Number

CAS 3029-19-4

TTD Drug ID

DMEF6IP

INTEDE Drug ID

DR2002

General Information of Drug (ID: DMEF6IP)

Molecule-Related Drug Atlas

Molecule Type:

DME

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Metabolized By Alcohol dehydrogenase class-I gamma (ADH1C)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[2]
octanol	DMBGHPE	Discovery agent	N.A.	Investigative	[1]
acetaldehyde	DMJFKG4	Discovery agent	N.A.	Investigative	[1]
Hydroxymethylpyrene	DMPGAR2	N. A.	N. A.	Investigative	[1]
BRN-2330710	DM87VP6	N. A.	N. A.	Investigative	[1]
Pyrenemethanol	DMGJ0RM	N. A.	N. A.	Investigative	[1]
Octanal	DMTN0OK	N. A.	N. A.	Investigative	[1]
------------------------------------------------------------------------------------


⏷ Show the Full List of 7 Drug(s)

Drug(s) Metabolized By Alcohol dehydrogenase class-II (ADH4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[1]
ANDROSTERONE	DMITJAK	N. A.	N. A.	Phase 3	[3]
octanol	DMBGHPE	Discovery agent	N.A.	Investigative	[1]
acetaldehyde	DMJFKG4	Discovery agent	N.A.	Investigative	[1]
Hydroxymethylpyrene	DMPGAR2	N. A.	N. A.	Investigative	[1]
BRN-2330710	DM87VP6	N. A.	N. A.	Investigative	[1]
Pyrenemethanol	DMGJ0RM	N. A.	N. A.	Investigative	[1]
Octanal	DMTN0OK	N. A.	N. A.	Investigative	[1]
------------------------------------------------------------------------------------


⏷ Show the Full List of 8 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Alcohol dehydrogenase class-II (ADH4)	DEOCWU3	ADH4_HUMAN	Substrate	[1]
Alcohol dehydrogenase class-I gamma (ADH1C)	DEM1HNL	ADH1G_HUMAN	Substrate	[1]

------------------------------------------------------------------------------------

References

1	Oxidation of alcohols and reduction of aldehydes derived from methyl- and dimethylpyrenes by cDNA-expressed human alcohol dehydrogenases. Toxicology. 2008 Mar 12;245(1-2):65-75.
2	Natural alcohol exposure: is ethanol the main substrate for alcohol dehydrogenases in animals? Chem Biol Interact. 2011 May 30;191(1-3):14-25.
3	13-cis-retinoic acid competitively inhibits 3 alpha-hydroxysteroid oxidation by retinol dehydrogenase RoDH-4: a mechanism for its anti-androgenic effects in sebaceous glands? Biochem Biophys Res Commun. 2003 Mar 28;303(1):273-8.