Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMEO3Y4)

Drug Name

ASN02563583 Drug Info

Synonyms

ASN 02563583; ASN-02563583

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Uracil nucleotide/cysteinyl leukotriene receptor (GPR17)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
LTE4	DMCPB0Q	Discovery agent	N.A.	Investigative	[3]
UDP-glucose	DMLT4JA	Discovery agent	N.A.	Investigative	[4]
LTC4	DM702WR	Discovery agent	N.A.	Investigative	[4]
LTD4	DMIUZX3	Discovery agent	N.A.	Investigative	[4]
ASN04421891	DMC82XN	Discovery agent	N.A.	Investigative	[2]
ASN04450772	DMKR69T	Discovery agent	N.A.	Investigative	[2]
ASN06917370	DMA20JP	Discovery agent	N.A.	Investigative	[2]
ASN04885796	DMQ0VZ8	Discovery agent	N.A.	Investigative	[2]
------------------------------------------------------------------------------------


⏷ Show the Full List of 8 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Uracil nucleotide/cysteinyl leukotriene receptor (GPR17)	TTMPART	GPR17_HUMAN	Agonist	[2]

------------------------------------------------------------------------------------

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5517).
2	In silico identification of new ligands for GPR17: a promising therapeutic target for neurodegenerative diseases. J Comput Aided Mol Des. 2011 Aug;25(8):743-52.
3	The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair. PLoS One. 2008;3(10):e3579.
4	The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor. EMBO J. 2006 Oct 4;25(19):4615-27.