Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMEU86T)

Drug Name

ACT017 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Cerebral ischemia	8B11	Phase 1/2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Platelet glycoprotein VI (GP6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Revacept	DMJ37UX	Arteriosclerosis	BD40	Phase 2	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT03803007) Acute Ischemic Stroke Interventional Study (ACTIMIS). U.S. National Institutes of Health.
2	Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT017, an Antiplatelet GPVI (Glycoprotein VI) Fab. Arterioscler Thromb Vasc Biol. 2019 May;39(5):956-964.
3	Novel antiplatelet drug revacept (Dimeric Glycoprotein VI-Fc) specifically and efficiently inhibited collagen-induced platelet aggregation without affecting general hemostasis in humans. Circulation.2011 May 3;123(17):1891-9.