General Information of Drug (ID: DMFJES5)

Drug Name
ISIS 100750 Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
TTD Drug ID
DMFJES5

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ISIS 100748 DMFW5VK Discovery agent N.A. Investigative [1]
ISIS 100742 DMIB6JL Discovery agent N.A. Investigative [1]
ISIS 100743 DMI7PGZ Discovery agent N.A. Investigative [1]
ISIS 100749 DMSMJ37 Discovery agent N.A. Investigative [1]
PMID18068976C25 DMTZQUJ Discovery agent N.A. Investigative [2]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
ADAM10 messenger RNA (ADAM10 mRNA) TTVXEGU ADA10_HUMAN Not Available [1]

References

1 US patent application no. 6,228,648, Antisense modulation of ADAM10 expression.
2 Conversion of an MMP-potent scaffold to an MMP-selective HER-2 sheddase inhibitor via scaffold hybridization and subtle P1' permutations. Bioorg Med Chem Lett. 2008 Jan 15;18(2):560-4.