General Information of Drug (ID: DMGULNZ)

Drug Name
BL-5040 Drug Info
Synonyms Leptin antagonist (anorexia), BioLineRx; Leptin antagonist (cachexia), BioLineRx; Leptin antagonist (inflammatory bowel disease), BioLineRx
Indication
Disease Entry ICD 11 Status REF
Cachexia MG20 Investigative [1]
Cross-matching ID
TTD Drug ID
DMGULNZ

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Drug(s) Targeting Leptin receptor (LEPR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metreleptin DM1NOEK Acquired generalized lipodystrophy Approved [2]
AMPE4L DM64X25 Diabetic complication 5A2Y Investigative [1]
PEGylated leptin DMZ01PS Obesity 5B81 Investigative [1]
ANG-2004 DMK1IMC Obesity 5B81 Investigative [1]
AMPSL DMXRIUT Diabetic complication 5A2Y Investigative [1]
Leptin DM5LY1H Alzheimer disease 8A20 Investigative [1]
EDP-21 DMMN0GO Obesity 5B81 Investigative [1]
AMPPL DMVHOQE Diabetic complication 5A2Y Investigative [1]
PEG-LPA-2 DMY293M Solid tumour/cancer 2A00-2F9Z Investigative [1]
⏷ Show the Full List of 9 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Leptin receptor (LEPR) TT0HD6V LEPR_HUMAN Antagonist [1]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1712).
2 2014 FDA drug approvals. Nat Rev Drug Discov. 2015 Feb;14(2):77-81.