Details of the Drug

General Information of Drug (ID: DMY293M)

Drug Name

PEG-LPA-2

Synonyms

Leptin receptor antagonists (cancer/endometriosis); Leptin receptor antagonists (cancer/endometriosis), CRT; Leptin receptor antagonists (cancer/endometriosis), Cancer Research Technology; PEGylated leptin receptor antagonists (cancer/endometriosis), CRT; PEGylated leptin receptor antagonists (cancer/endometriosis), Cancer Research Technology

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Investigative	[1]
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Cross-matching ID

TTD ID: D0J3AV

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Leptin receptor (LEPR)	TT0HD6V	LEPR_HUMAN	Antagonist	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Solid tumour/cancer

ICD Disease Classification

2A00-2F9Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Leptin receptor (LEPR)	DTT	LEPR	5.82E-02	0.05	0.15

Molecular Expression Atlas (MEA)

MEA Detail

Jump to Detail Molecular Expression Atlas of This Drug

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1712).