General Information of Drug (ID: DMI15VQ)

Drug Name
4-((+/-)-(1H-imidazol-1-yl)-(E)-methylretinoate Drug Info
Synonyms CHEMBL224828; 4-((+/-)-(1H-imidazol-1-yl)-(E)-methylretinoate; BDBM50158415; 4-(1-Imidazolyl)retinoic acid methyl ester
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
10786043
TTD Drug ID
DMI15VQ

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
LIAROZOLE DM4OYXE Dermatological disease DA24.Y Phase 2/3 [2]
Rambazole DMP2DNS Psoriasis vulgaris EA90 Phase 2 [3]
4-((+/-)-(1H-imidazol-1-yl)-(E)-retinoic acid DMKYB4D Discovery agent N.A. Investigative [1]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cytochrome P450 26 (CYP26A1) TTD7Q0R CP26A_HUMAN Inhibitor [1]

References

1 Novel retinoic acid metabolism blocking agents endowed with multiple biological activities are efficient growth inhibitors of human breast and pros... J Med Chem. 2004 Dec 30;47(27):6716-29.
2 Novel azolyl-(phenylmethyl)]aryl/heteroarylamines: potent CYP26 inhibitors and enhancers of all-trans retinoic acid activity in neuroblastoma cells. Bioorg Med Chem. 2008 Sep 1;16(17):8301-13.
3 Emerging drugs for psoriasis. Expert Opin Emerg Drugs. 2009 Mar;14(1):145-63.