Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJ3KPO)

Drug Name
TD-101 Drug Info
Indication
Disease Entry ICD 11 Status REF
Flavivirus infection 1C80 Phase 2 [1]
Pachyonychia EE10.3 Phase 1 [2]
Cross-matching ID
TTD Drug ID
DMJ3KPO

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Keratin 6A messenger RNA (KRT6A mRNA) TT2FX8W K2C6A_HUMAN Not Available [3]

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 ClinicalTrials.gov (NCT00716014) Study of TD101, a Small Interfering RNA (siRNA) Designed for Treatment of Pachyonychia Congenita. U.S. National Institutes of Health.
3 First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder. Mol Ther. 2010 Feb;18(2):442-6.