General Information of Drug (ID: DMK3UJY)

Drug Name
Macrocycle derivative 5 Drug Info
Synonyms PMID30107136-Compound-Example69
Indication
Disease Entry ICD 11 Status REF
Hepatitis DB97.Z Patented [1]
Human immunodeficiency virus infection 1C62 Patented [1]
Infectious disease 1A00-CA43.1 Patented [1]
Solid tumour/cancer 2A00-2F9Z Patented [1]
Cross-matching ID
TTD Drug ID
DMK3UJY

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Macrocycle derivative 6 DMQ84KW Hepatitis DB97.Z Patented [1]
PMID30107136-Compound-Example12 DMN2K10 Hepatitis DB97.Z Patented [1]
Macrocycle derivative 1 DMN7I9C Hepatitis DB97.Z Patented [1]
Macrocycle derivative 9 DMARU0E Hepatitis DB97.Z Patented [1]
Macrocycle derivative 2 DM5OEQZ Hepatitis DB97.Z Patented [1]
Biaryl compound 1 DMHEAJQ Hepatitis DB97.Z Patented [1]
Macrocycle derivative 3 DMYGFTI Hepatitis DB97.Z Patented [1]
PMID30107136-Compound-Example11 DMD65GU Hepatitis DB97.Z Patented [1]
Macrocycle derivative 8 DMOMTBE Hepatitis DB97.Z Patented [1]
Biaryl compound 2 DMS8VYE Hepatitis DB97.Z Patented [1]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Macrocycle derivative 6 DMQ84KW Hepatitis DB97.Z Patented [1]
PMID30107136-Compound-Example12 DMN2K10 Hepatitis DB97.Z Patented [1]
Macrocycle derivative 1 DMN7I9C Hepatitis DB97.Z Patented [1]
Macrocycle derivative 9 DMARU0E Hepatitis DB97.Z Patented [1]
Macrocycle derivative 2 DM5OEQZ Hepatitis DB97.Z Patented [1]
Biaryl compound 1 DMHEAJQ Hepatitis DB97.Z Patented [1]
Macrocycle derivative 3 DMYGFTI Hepatitis DB97.Z Patented [1]
PMID30107136-Compound-Example11 DMD65GU Hepatitis DB97.Z Patented [1]
Macrocycle derivative 8 DMOMTBE Hepatitis DB97.Z Patented [1]
Biaryl compound 2 DMS8VYE Hepatitis DB97.Z Patented [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
CD80-PD-L1 interaction (CD80/PD-L1 PPI) TT5YPJF CD80_HUMAN-PD1L1_HUMAN Inhibitor [1]
PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) TT23XQV PDCD1_HUMAN-PD1L1_HUMAN Inhibitor [1]

References

1 A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018).Expert Opin Ther Pat. 2018 Sep;28(9):665-678.