Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMK3UJY)

Drug Name
Macrocycle derivative 5 Drug Info
Synonyms PMID30107136-Compound-Example69
Indication
Disease Entry ICD 11 Status REF
Hepatitis DB97.Z Patented [1]
Human immunodeficiency virus infection 1C62 Patented [1]
Infectious disease 1A00-CA43.1 Patented [1]
Solid tumour/cancer 2A00-2F9Z Patented [1]
Cross-matching ID
TTD Drug ID
DMK3UJY

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting PD-1-PD-L1 interaction (PD-1/PD-L1 PPI)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Macrocycle derivative 6 DMQ84KW Hepatitis DB97.Z Patented [1]
PMID30107136-Compound-Example12 DMN2K10 Hepatitis DB97.Z Patented [1]
Macrocycle derivative 1 DMN7I9C Hepatitis DB97.Z Patented [1]
Macrocycle derivative 9 DMARU0E Hepatitis DB97.Z Patented [1]
Macrocycle derivative 2 DM5OEQZ Hepatitis DB97.Z Patented [1]
Biaryl compound 1 DMHEAJQ Hepatitis DB97.Z Patented [1]
Macrocycle derivative 3 DMYGFTI Hepatitis DB97.Z Patented [1]
PMID30107136-Compound-Example11 DMD65GU Hepatitis DB97.Z Patented [1]
Macrocycle derivative 8 DMOMTBE Hepatitis DB97.Z Patented [1]
Biaryl compound 2 DMS8VYE Hepatitis DB97.Z Patented [1]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting CD80-PD-L1 interaction (CD80/PD-L1 PPI)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Macrocycle derivative 6 DMQ84KW Hepatitis DB97.Z Patented [1]
PMID30107136-Compound-Example12 DMN2K10 Hepatitis DB97.Z Patented [1]
Macrocycle derivative 1 DMN7I9C Hepatitis DB97.Z Patented [1]
Macrocycle derivative 9 DMARU0E Hepatitis DB97.Z Patented [1]
Macrocycle derivative 2 DM5OEQZ Hepatitis DB97.Z Patented [1]
Biaryl compound 1 DMHEAJQ Hepatitis DB97.Z Patented [1]
Macrocycle derivative 3 DMYGFTI Hepatitis DB97.Z Patented [1]
PMID30107136-Compound-Example11 DMD65GU Hepatitis DB97.Z Patented [1]
Macrocycle derivative 8 DMOMTBE Hepatitis DB97.Z Patented [1]
Biaryl compound 2 DMS8VYE Hepatitis DB97.Z Patented [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
CD80-PD-L1 interaction (CD80/PD-L1 PPI) TT5YPJF CD80_HUMAN-PD1L1_HUMAN Inhibitor [1]
PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) TT23XQV PDCD1_HUMAN-PD1L1_HUMAN Inhibitor [1]

References

1 A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018).Expert Opin Ther Pat. 2018 Sep;28(9):665-678.