Details of the Drug-Related molecule(s) Interaction Atlas

Aspartic acid Drug Info

(2S)-2-aminobutanedioic acid; (2S)-Aspartic acid; (S)-2-Aminosuccinic acid; (S)-Aminobutanedioic acid; (S)-Aspartic acid; Acidum asparticum; Aminosuccinic acid; Asparagic acid; Asparaginic acid; Asparaginsaeure [German]; Aspartate, L-; Aspartic acid, L-; Aspatofort; Butanedioic acid, amino-, (S); H-Asp-OH; L-(+)-Aspartic acid; L-2-Aminobutanedioic acid; L-Aminosuccinic acid; L-Asp; L-Asparagic acid; L-Asparaginic acid; L-Asparaginsaeure; L-Asparaginsyra; L-Aspartinsaeure; L-aspartate; L-aspartic acid; aspartate; aspartic acid

Cross-matching ID

PubChem CID

5960

ChEBI ID

ChEBI:17053

CAS Number

CAS 56-84-8

TTD Drug ID

DMK7EYA

VARIDT Drug ID

DR00352

General Information of Drug (ID: DMK7EYA)

Molecule-Related Drug Atlas

Molecule Type:

DTP

Drug Status:

Approved Drug(s)

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Drug(s) Transported By Organic cation transporter-like 3 (SLC22A13)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
L-Glutamic Acid	DM4PUDW	Schizophrenia	6A20	Approved	[1]
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Drug(s) Transported By Putative sodium-coupled neutral amino acid transporter 10 (SLC38A10)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
L-Glutamic Acid	DM4PUDW	Schizophrenia	6A20	Approved	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Organic cation transporter-like 3 (SLC22A13)	DT38SZL	S22AD_HUMAN	Substrate	[1]
Putative sodium-coupled neutral amino acid transporter 10 (SLC38A10)	DT2LGOY	S38AA_HUMAN	Substrate	[2]

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References

1	SLC22A13 catalyses unidirectional efflux of aspartate and glutamate at the basolateral membrane of type A intercalated cells in the renal collecting duct. Biochem J. 2014 Jan 15;457(2):243-51.
2	The neuronal and astrocytic protein SLC38A10 transports glutamine, glutamate, and aspartate, suggesting a role in neurotransmission. FEBS Open Bio. 2017 Apr 26;7(6):730-746.