Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DML29RF)

Drug Name

KP-100 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Type-1 diabetes	5A10	Phase 1/2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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Drug(s) Targeting Protein tyrosine phosphatase (PTP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
INCB13739	DMLQ3PO	Type-2 diabetes	5A11	Phase 2a	[3]
Pervanadate	DM873BS	Discovery agent	N.A.	Investigative	[3]
Diamide	DMOCQ9J	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Protein tyrosine phosphatase (PTP)	TTWC6MY	NOUNIPROTAC	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT02193334) Phase I/II Study of KP-100IT in Acute Spinal Cord Injury. U.S. National Institutes of Health.
2	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010512)
3	Induction of endothelial cell surface adhesion molecules by tumor necrosis factor is blocked by protein tyrosine phosphatase inhibitors: role of the nuclear transcription factor NF-kappa B. Eur J Immunol. 1997 Sep;27(9):2172-9.