Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMLQK6E)

Drug Name

PYM-50028 Drug Info

Synonyms

Cogane; Smilagenin; P-58; P-63

Indication

Disease Entry	ICD 11	Status	REF
Neurological disorder	6B60	Phase 2	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Brain-derived neurotrophic factor (BDNF)	TTSMLOH	BDNF_HUMAN	Agonist	[1]

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References

1	PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease. FASEB J. 2008 Jul;22(7):2488-97.