Details of the Drug

General Information of Drug (ID: DMLQK6E)

Drug Name

PYM-50028

Synonyms

Cogane; Smilagenin; P-58; P-63

Indication

Disease Entry	ICD 11	Status	REF
Neurological disorder	6B60	Phase 2	[1]
------------------------------------------------------------------------------------

Structure

3D Structure is Not Available

3D MOL

2D MOL

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Brain-derived neurotrophic factor (BDNF)	TTSMLOH	BDNF_HUMAN	Agonist	[1]

------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease. FASEB J. 2008 Jul;22(7):2488-97.