General Information of Drug (ID: DMNF70P)

Drug Name
IS1 Drug Info
Synonyms
N-{2-Furan-2-yl-1-[(pyridin-3-ylmethyl)-carbamoyl]-vinyl}-benzamide; IS1; AC1MFOLV; SMR000176552; Salor-int l253618-1ea; MLS000551960; GTPL8517; CHEMBL1499206; SCHEMBL10092076; MolPort-000-526-523; HMS2374A20; ZINC4892255; AKOS000531713; BAS 01151561; ACM324562018; ST053578; SR-01000425582; SR-01000425582-1; N-[(Z)-1-furan-2-yl-3-oxo-3-(pyridin-3-ylmethylamino)prop-1-en-2-yl]benzamide; N~1~-((Z)-2-(2-furyl)-1-{[(3-pyridylmethyl)amino]carbonyl}-1-ethenyl)benzamide
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
2874943
TTD Drug ID
DMNF70P

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
US9475795, 80 DM0ZDL3 N. A. N. A. Patented [3]
ZINC19658740 DMLZDAK N. A. N. A. Patented [4]
US9475795, 89 DMR6ODL N. A. N. A. Patented [3]
US9475795, 19 DMGPDEF N. A. N. A. Patented [3]
triazine compound PC10 DMCLA2D Discovery agent N.A. Investigative [5]
IS20 DMQ5GA9 Discovery agent N.A. Investigative [2]
⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prokineticin receptor-1 (PROKR1) TTB9CIL PKR1_HUMAN Agonist [2]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8517).
2 Discovery and cardioprotective effects of the first non-Peptide agonists of the G protein-coupled prokineticin receptor-1. PLoS One. 2015 Apr 1;10(4):e0121027.
3 Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases. US9475795.
4 Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases. US10167273.
5 Prokineticin receptor 1 antagonist PC-10 as a biomarker for imaging inflammatory pain. J Nucl Med. 2011 Apr;52(4):600-7.