Details of the Drug-Related molecule(s) Interaction Atlas

D-glucose 6-phosphate Drug Info

Aldohexose 6-phosphate; D(+)-Glucopyranose 6-phosphate; D-Glucose 6-phosphate; D-Glucose 6-phosphoric acid; D-glucose-6-phosphate; SCHEMBL6599; VFRROHXSMXFLSN-SLPGGIOYSA-N; ZINC19850142; glucose-6 phosphate; (2R,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexyl dihydrogen phosphate; 375AW34SQA; 56-73-5; 6-O-phosphono-D-glucose; AC1L98E0; CHEBI:15954; CTK3I9725; UNII-375AW34SQA; [(2R,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexyl] dihydrogen phosphate; aldehydo-D-glucose 6-(dihydrogen phosphate); aldehydo-D-glucose 6-phosphate

Cross-matching ID

PubChem CID

439958

ChEBI ID

CHEBI:15954

CAS Number

CAS 56-73-5

TTD Drug ID

DMNRW57

INTEDE Drug ID

DR2083

General Information of Drug (ID: DMNRW57)

Molecule-Related Drug Atlas

Molecule Type:

DME

DOT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Investigative Drug(s)

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Drug(s) Affected By Glucose-6-phosphatase 2 (G6PC2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[3]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[4]
(11-BETA)-11,21-DIHYDROXY-PREGN-4-ENE-3,20-DIONE	DMTPQ84	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Glucose-6-phosphatase beta (G6PC3)^{Main DME}	DEE1B8O	G6PC3_HUMAN	Substrate	[1]

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Drug Off-Target (DOT)

References

1	Identification and characterisation of a new human glucose-6-phosphatase isoform. FEBS Lett. 2003 Sep 11;551(1-3):159-64.
2	Enzymatic characterization of the pancreatic islet-specific glucose-6-phosphatase-related protein (IGRP). J Biol Chem. 2004 Apr 2;279(14):13976-83. doi: 10.1074/jbc.M307756200. Epub 2004 Jan 13.
3	G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to Stress. Endocrinology. 2016 Aug;157(8):3002-8. doi: 10.1210/en.2016-1245. Epub 2016 Jun 14.
4	Air pollution and DNA methylation alterations in lung cancer: A systematic and comparative study. Oncotarget. 2017 Jan 3;8(1):1369-1391. doi: 10.18632/oncotarget.13622.