General Information of Drug (ID: DMPDF9B)

Drug Name
US9006244, E2a Drug Info
Synonyms SCHEMBL15272683; CHEMBL3672844; US9006244, E2a
Cross-matching ID
PubChem CID
71735263
TTD Drug ID
DMPDF9B

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
US9073931, E2 DMK9FJG N. A. N. A. Patented [2]
BDBM50177019 DMEL28G N. A. N. A. Patented [3]
US9006244, E2b DMP0TBO N. A. N. A. Patented [1]
US9073931, E1 DM2Z43I N. A. N. A. Patented [2]
US9006244, E1 DMBF1C0 N. A. N. A. Patented [1]
BDBM50177012 DM52IQF N. A. N. A. Patented [3]
67S DMJL1MB N. A. N. A. Patented [3]
US9073931, E3 DMCYM8P N. A. N. A. Patented [2]
desmosterol DMV8SUM Discovery agent N.A. Investigative [4]
L-783483 DM6OTGE Discovery agent N.A. Investigative [5]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Oxysterols receptor LXR-alpha (NR1H3) TTECBXN NR1H3_HUMAN Inhibitor [1]

References

1 Liver X receptor modulators. US9006244.
2 Liver X receptor modulators. US9073931.
3 Piperazine derivatives as liver X receptor modulators. US10144715.
4 Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands. J Biol Chem. 2006 Sep 22;281(38):27816-26.
5 A novel liver X receptor agonist establishes species differences in the regulation of cholesterol 7alpha-hydroxylase (CYP7a). Endocrinology. 2002 Jul;143(7):2548-58.