General Information of Drug (ID: DMPIV1G)

Drug Name
Ilatreotide Drug Info
Synonyms SDZ-CO-611
Indication
Disease Entry ICD 11 Status REF
Duodenal ulcer DA63 Investigative [1]
Cross-matching ID
PubChem CID
72046
CAS Number
CAS 119719-11-8
TTD Drug ID
DMPIV1G

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
177Lu-DOTA-octreotate DMP5L8S Melanoma 2C30 Phase 3 [2]
177-Lu-oxodotreotide DMMZS2T Neuroendocrine cancer 2B72.1 Phase 3 [3]
177Lu-DOTATATE DMT8GVU Hepatitis C virus infection 1E51.1 Phase 2 [2]
Somatoprim DMTVS3A Acromegaly 5A60.0 Phase 2 [4]
Edotreotide DMQ08AJ Acromegaly 5A60.0 Phase 2 [5]
FK-962 DMV0MZ3 Alzheimer disease 8A20 Phase 2 [6]
177Lu-labelled DOTA-JR11 DMVZ9XL Neuroendocrine cancer 2B72.1 Phase 1/2 [7]
212Pb-labelled DOTAMTATE DMN9MPX Neuroendocrine cancer 2B72.1 Phase 1 [8]
AlphaMedix DMBVM1Q Neuroendocrine cancer 2B72.1 Phase 1 [9]
FK-960 DMPD8O2 Cognitive impairment 6D71 Discontinued in Phase 2 [6]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Somatostatin receptor (SSTR) TTOMNR9 NOUNIPROTAC Modulator [1]

References

1 Inhibitory effect of intraduodenal administration of somatostatin analogue SDZ CO 611 on rat pancreatic exocrine secretion. Pancreas. 1993 Jul;8(4):471-5.
2 Peptide receptor radionuclide therapy with 177Lu-DOTATATE for patients with somatostatin receptor-expressing neuroendocrine tumors: the first US phase 2 experience. Pancreas. 2014 May;43(4):518-25.
3 Lutetium-labelled peptides for therapy of neuroendocrine tumours. Eur J Nucl Med Mol Imaging. 2012 Feb;39 Suppl 1(Suppl 1):S103-12.
4 DG3173 (somatoprim), a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue, effectively reduces GH secretion in human GH-secreting pituitary adenomas even in Octreotide non-responsive tumours.Eur J Endocrinol.2012 Feb;166(2):223-34.
5 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
6 FK960, a novel potential anti-dementia drug, enhances high K(+)-evoked release of somatostatin from rat hippocampal slices. Brain Res. 2001 Feb 16;892(1):111-7.
7 Multimodal Imaging of 2-Cycle PRRT with 177 Lu-DOTA-JR11 and 177 Lu-DOTATOC in an Orthotopic Neuroendocrine Xenograft Tumor Mouse Model. J Nucl Med. 2021 Mar;62(3):393-398.
8 Radiopharmaceutical therapy in cancer: clinical advances and challenges. Nat Rev Drug Discov. 2020 Sep;19(9):589-608.
9 Clinical pipeline report, company report or official report of Orano Med.