Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPUKA7)

Drug Name

Caplacizumab Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Thrombotic thrombocytopenic purpura	3B64.14	Approved	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Discontinued Drug(s)

Investigative Drug(s)

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Drug(s) Targeting von Willebrand factor (VWF)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Vonvendi	DMI783H	Von willebrand disease	3B12	Approved	[2]
Recombinant von Willebrand factor/recombinant Factor VIII complex	DM7JFDO	Von willebrand disease	3B12	Phase 3	[3]
ALX-0081	DM7EBH9	Thrombotic thrombocytopenic purpura	3B64.14	Phase 3	[4]
ARC1779	DM7PCLY	Intracranial embolism	8B22.1	Phase 2	[5]
BT-200	DM1EYOF	Von willebrand disease	3B12	Phase 2	[6]
DA-697b	DMBRN2G	Thrombosis	DB61-GB90	Phase 1	[7]
DTRI-031	DM0BCT7	Ischemic stroke	8B11.5Z	Phase 1	[8]
Mitoflaxone	DMO06JV	Solid tumour/cancer	2A00-2F9Z	Terminated	[9]
Auryntricarboxylic acid (ATA)	DMOIQ4K	Discovery agent	N.A.	Investigative	[9]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2019
2	Clinical pipeline report, company report or official report of Vonvendi.
3	6 Factor VIII Concentrates, Factor VIII/von Willebrand Factor Concentrates, Factor IX Concentrates, Activated Prothrombin Complex Concentrates. Transfus Med Hemother. 2009 December; 36(6): 409-418.
4	Clinical pipeline report, company report or official report of Ablynx
5	Short-Acting Anti-VWF (von Willebrand Factor) Aptamer Improves the Recovery, Survival, and Hemostatic Functions of Refrigerated Platelets. Arterioscler Thromb Vasc Biol. 2019 Oct;39(10):2028-2037.
6	Clinical pipeline report, company report or official report of Guardian Theapeutics
7	A new oral antiplatelet agent with potent antithrombotic properties: comparison of DZ-697b with clopidogrel a randomised phase I study. Thromb Haemost. 2010 Jan;103(1):205-12.
8	Clinical pipeline report, company report or official report of Basking Biosciences
9	Novel approaches to the treatment of thrombosis. Trends Pharmacol Sci. 2002 Jan;23(1):25-32.