Details of the Drug-Related molecule(s) Interaction Atlas

US9714230, 46 Drug Info

SCHEMBL15778753; MITOFELVTHNBGA-UHFFFAOYSA-N; BDBM263981; US9714230, 46; 2-(5-(4-bromophenyl)-1H-pyrazol- 1-yl)isonicotinic acid; 2-[5-(4-bromophenyl)-1H-pyrazol-1-yl]pyridine-4-carboxylic acid

Cross-matching ID

PubChem CID

86725517

TTD Drug ID

DMPZS16

General Information of Drug (ID: DMPZS16)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

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Drug(s) Targeting Lysine-specific demethylase 5A (KDM5A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
6EP	DMN082G	N. A.	N. A.	Patented	[2]
BDBM50158803	DMTWI1H	N. A.	N. A.	Patented	[3]
US10022354, Example 151	DMVCWXD	N. A.	N. A.	Patented	[4]
US9714230, 12	DMEB59T	N. A.	N. A.	Patented	[2]
BDBM50158791	DMU07MO	N. A.	N. A.	Patented	[5]
US10040779, Example 4	DMWDGCH	N. A.	N. A.	Patented	[6]
US9611221, Example 9	DMSD354	N. A.	N. A.	Patented	[7]
BDBM50158794	DMWJZU9	N. A.	N. A.	Patented	[6]
BDBM50158703	DMS7ZLK	N. A.	N. A.	Patented	[2]
AKOS020330656	DMNIE4M	N. A.	N. A.	Patented	[8]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Lysine-specific demethylase 5A (KDM5A)	TTIG67W	KDM5A_HUMAN	Inhibitor	[1]

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References

1	Histone demethylase inhibitors. US9604961.
2	Histone demethylase inhibitors. US9714230.
3	Histone demethylase inhibitors. US9617242.
4	IRE-1 inhibitors
5	Histone demethylase inhibitors. US9725441.
6	Histone demethylase inhibitors. US10040779.
7	Histone demethylase inhibitors. US9611221.
8	Histone demethylase inhibitors. US10179769.