Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMQ9USH)

Drug Name
Propandiamine Drug Info
Synonyms
1,3-Diaminopropane; Propane-1,3-diamine; Trimethylenediamine; XFNJVJPLKCPIBV-UHFFFAOYSA-N; aminopropylamine; 1,3-Propane-diamine; 1,3-Propanediamine; 1,3-Propylenediamine; 1,3-diaminepropane; 1,3-diaminopropan; 1,3-diaminopropane; 1,3-propandiamine; 1,3-propane diamine; 1,3diaminopropane; 1.3-diaminopropane; 109-76-2; 3-Aminopropylamine; AI3-25358; BRN 0605277; C00986; CB3ISL56KG; CCRIS 4054; CHEBI:15725; EINECS 203-702-7; EINECS 268-600-7; H2N(CH2)3NH2; MFCD00008228; NSC 8154; UNII-CB3ISL56KG; a,w-Propanediamine; alpha,omega-Propanediamine
Cross-matching ID
PubChem CID
428
ChEBI ID
CHEBI:35411
CAS Number
CAS 109-76-2
TTD Drug ID
DMQ9USH
INTEDE Drug ID
DR2028

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DME
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Metabolized By Putrescine acetyltransferase (SSAT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Spermidine DMVJNFI Plaque psoriasis EA90.0 Phase 3 [2]
SPERMINE DMD4BFY N. A. N. A. Terminated [1]
N1-(2-aminoethyl)ethane-1,2-diamine DM6HM5S Discovery agent N.A. Investigative [1]
Ethylene diamine DMBULX4 Tuberculosis 1B10-1B1Z Investigative [1]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Putrescine acetyltransferase (SSAT1) Main DME DEMWO83 SAT1_HUMAN Substrate [1]

References

1 Mechanistic and structural analysis of human spermidine/spermine N1-acetyltransferase. Biochemistry. 2007 Jun 19;46(24):7187-95.
2 The use of novel C-methylated spermidine derivatives to investigate the regulation of polyamine metabolism. J Med Chem. 2011 Jul 14;54(13):4611-8.