General Information of Drug (ID: DMQCHU3)

Drug Name
CPP -15 Drug Info
Synonyms CPP-15
Indication
Disease Entry ICD 11 Status REF
Infantile spasm 8A62.0 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMQCHU3

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Drug(s) Targeting GABA transaminase (ABAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
L-Alanine DMZDN4W Dietary shortage 5B5K Approved [3]
Pyridoxal Phosphate DMO2K0J Malnutrition 5B50-5B71 Approved [3]
Pyruvic acid DM7Q41G Malnutrition 5B50-5B71 Approved [3]
Vigabatrin DMYT0OG Alcohol dependence 6C40.2 Approved [4]
Divalproex sodium DM4RK0G Seizure disorder 8A6Z Approved [3]
CPP-115 DMK9NQI Tourette syndrome 8A05.00 Phase 2 [2]
K-828-AB DMJLNZQ Dementia 6D80-6D86 Phase 2 [5]
T83193 DMHO29Y Discovery agent N.A. Patented [6]
4-hydroxybenzaldehyde DM471P5 Discovery agent N.A. Patented [7]
Acetate Ion DMD08RH Discovery agent N.A. Investigative [8]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
GABA transaminase (ABAT) TTT2LD9 GABT_HUMAN Modulator [2]

References

1 Clinical pipeline report, company report or official report of Catalyst Pharma.
2 Clinical pipeline report, company report or official report of Catalyst Pharma.
3 DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6.
4 Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
5 Phase II clinical trial of K-828-AB for treating behavioral and psychological symptoms of dementia. Kowa Co. Ltd.
6 Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives. Bioorg Med Chem Lett. 2006 Feb;16(3):592-5.
7 Inactivation of GABA transaminase by 3-chloro-1-(4-hydroxyphenyl)propan-1-one. Bioorg Med Chem Lett. 2009 Feb 1;19(3):731-4.
8 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.