Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMRJK3U)

Drug Name

Avotermin Drug Info

Synonyms

Juvista; RN-1001; SPD-538; TGF3, Renovo; RN-1, Renovo

Indication

Disease Entry	ICD 11	Status	REF
Sarcoidosis	4B20.5	Phase 3	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Transforming growth factor beta 3 (TGFB3)	TTWOMY8	TGFB3_HUMAN	Modulator	[2]

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References

1	ClinicalTrials.gov (NCT00742443) Juvista in Scar Revision Surgery of Disfiguring Scars. U.S. National Institutes of Health.
2	Discovery and development of avotermin (recombinant human transforming growth factor beta 3): a new class of prophylactic therapeutic for the improvement of scarring. Wound Repair Regen. 2011 Sep;19 Suppl 1:s38-48.