Details of the Drug

General Information of Drug (ID: DMRJK3U)

Drug Name

Avotermin

Synonyms

Juvista; RN-1001; SPD-538; TGF3, Renovo; RN-1, Renovo

Indication

Disease Entry	ICD 11	Status	REF
Sarcoidosis	4B20.5	Phase 3	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Transforming growth factor beta 3 (TGFB3)	TTWOMY8	TGFB3_HUMAN	Modulator	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT00742443) Juvista in Scar Revision Surgery of Disfiguring Scars. U.S. National Institutes of Health.
2	Discovery and development of avotermin (recombinant human transforming growth factor beta 3): a new class of prophylactic therapeutic for the improvement of scarring. Wound Repair Regen. 2011 Sep;19 Suppl 1:s38-48.