Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMRKA08)

Drug Name
Oxolithocholic acid Drug Info
Synonyms
12-Ketolithocholic acid; 12-Oxolithocholic acid; 12-Oxolithocholate; 3?-Hydroxy-12 Ketolithocholic Acid; 3alpha-Hydroxy-12-0X0-5beta-cholanoic acid; 3alpha-Hydroxy-12-oxo-5beta-cholan-24-oic Acid; 5130-29-0; 57668172Z5; CCRIS 3990; Cholan-24-oic acid, 3-hydroxy-12-oxo-, (3alpha,5beta)-; UNII-57668172Z5; (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid; 12-Dehydrodeoxycholic acid; 12-Ketodeoxycholic acid
Cross-matching ID
PubChem CID
3080612
ChEBI ID
CHEBI:139134
CAS Number
CAS 5130-29-0
TTD Drug ID
DMRKA08
INTEDE Drug ID
DR2625

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Alpha-hydroxysteroid dehydrogenase (12AH) DEL5PTS 12AH_CLOS4 Substrate [1]
Alpha-hydroxysteroid dehydrogenase (12AH) DEOIYWD 12AH_CLOS4 Substrate [1]
Alpha-hydroxysteroid dehydrogenase (12AH) DER7IAK 12AH_CLOS4 Substrate [1]
Alpha-hydroxysteroid dehydrogenase (12AH) DE5Q9XD 12AH_CLOS4 Substrate [1]

References

1 Metabolism of oxo-bile acids and characterization of recombinant 12alpha-hydroxysteroid dehydrogenases from bile acid 7alpha-dehydroxylating human gut bacteria. Appl Environ Microbiol. 2018 May 1;84(10). pii: e00235-18.