General Information of Drug (ID: DMTB91D)

Drug Name
5-tosyl-5H-dibenzo[b,d]azepin-7(6H)-one Drug Info
Synonyms
CHEMBL498086; 24127-35-3; KCIOJLFKVQHRPU-UHFFFAOYSA-N; 5,6-dihydro-5-(p-tolylsulfonyl)-7h-dibenz[b,d]azepin-7-one; 5-tosyl-5H-dibenzo[b,d]azepin-7(6H)-one; AC1LCKZQ; TimTec1_004880; Oprea1_188679; SCHEMBL3034555; CTK8H7702; HMS1547N18; 7H-Dibenz[b,d]azepin-7-one, 5,6-dihydro-5-(p-tolylsulfonyl)-; BDBM50279063; KB-310270; 5-(4-methylphenyl)sulfonyl-6H-benzo[d][1]benzazepin-7-one; 5-(Toluene-4-sulfonyl)-5,6-dihydro-dibenzo[b,d]azepin-7-one; 5-[(4-Methylphenyl)sulfonyl]-5,6-dihydro-7H-dibenzo[b,d]azepin-7-one #
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
602095
TTD Drug ID
DMTB91D

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Chlorzoxazone DMCYVDT Acute pain MG31 Approved [2]
Charybdotoxin DMKN345 Scorpion envenoming syndrome 8D43 Approved [3]
ICA-17043 DMRFY7I Alzheimer disease 8A20 Phase 2 [4]
4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one DMKMH5L Discovery agent N.A. Investigative [1]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DMQEJVU Conjunctival fibrosis 9A61.3 Investigative [1]
4-fluorophenyl-2,2-diphenylacetamide DMI03KV Discovery agent N.A. Investigative [4]
N-methyl-2,2,2-triphenylacetamide DMQGRMO Discovery agent N.A. Investigative [4]
TRIPHENYLMETHANAMINE DM3CQIZ Discovery agent N.A. Investigative [4]
N,N-dimethyl-2,2,2-triphenylacetamide DM9XZJN Discovery agent N.A. Investigative [4]
(2-fluorophenyl)-(4-fluorophenyl)phenylacetamide DMFV76H Discovery agent N.A. Investigative [4]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Calcium-activated potassium channel (KCN) TTMNI76 NOUNIPROTAC Inhibitor [1]

References

1 Inhibitors of potassium channels KV1.3 and IK-1 as immunosuppressants. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2299-304.
2 Chlorzoxazone inhibits contraction of rat thoracic aorta. Eur J Pharmacol. 2006 Sep 18;545(2-3):161-6.
3 Reversible inhibition of the platelet procoagulant response through manipulation of the Gardos channel. Blood. 2006 Oct 1;108(7):2223-8.
4 Novel inhibitors of the Gardos channel for the treatment of sickle cell disease. J Med Chem. 2008 Feb 28;51(4):976-82.