Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMU6CQ7)

Drug Name

NHS-IL 12 Drug Info

Synonyms

NHS-IL12

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Interleukin-12 beta (IL12B)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Isoproterenol	DMK7MEY	Atrioventricular block		Approved	[3]
ABT-874	DMYHSO2	Plaque psoriasis	EA90.0	Phase 3	[4]
EGEN-001	DM6L5TR	Fallopian tube cancer	2C74	Phase 2	[5]
SFV IL-12 gene therapy	DMVIWNK	Breast cancer	2C60-2C65	Phase 2	[6]
Ad-IL-12 DNA therapeutic	DMB19IO	Melanoma	2C30	Phase 1/2	[7]
PF-07261271	DM0K4WQ	Inflammatory bowel disease	DD72	Phase 1	[8]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT01417546) NHS-IL12 for Solid Tumors. U.S. National Institutes of Health.
2	The immunocytokine NHS-IL12 as a potential cancer therapeutic. Oncotarget. 2014 Apr 15;5(7):1869-84.
3	A phase 1 study of AS1409, a novel antibody-cytokine fusion protein, in patients with malignant melanoma or renal cell carcinoma. Clin Cancer Res. 2011 Apr 1;17(7):1998-2005.
4	Briakinumab for the treatment of plaque psoriasis.BioDrugs.2012 Feb 1;26(1):9-20.
5	National Cancer Institute Drug Dictionary (drug id 454593).
6	Clinical pipeline report, company report or official report of Trademarkia.
7	National Cancer Institute Drug Dictionary (drug id 710508).
8	Clinical pipeline report, company report or official report of Pfizer