Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMUVON0)

Drug Name

PNT-2258 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Diffuse large B-cell lymphoma	2A81	Phase 2	[1]
Solid tumour/cancer	2A00-2F9Z	Phase 2	[2]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting BCL-2 messenger RNA (BCL2 mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Beclanorsen	DMXVRI0	leukaemia	2A60-2B33	Phase 1/2	[4]
BP1002	DMI826O	Haematopoietic/lymphoid cancer	2B33.5	Phase 1	[5]
BP-100-1.02	DMGEYFB	Lymphoma	2A80-2A86	Investigative	[6]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	ClinicalTrials.gov (NCT01733238) Study of PNT2258 for Treatment of Relapsed or Refractory Non-Hodgkin's Lymphoma. U.S. National Institutes of Health.
3	Clinical pipeline report, company report or official report of ProNAi.
4	Combination of novel imidazopyridazine mps-1 kinase inhibitors and bcl-2 family protein inhibitors. ACS Med Chem Lett. 2014 Jul 30;6(1):7-8.
5	Clinical pipeline report, company report or official report of Bio-Path Holdings.
6	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2844).