General Information of Drug (ID: DMUWO6D)

Drug Name
BIBF100 Drug Info
Indication
Disease Entry ICD 11 Status REF
Multiple myeloma 2A83 Investigative [1]
Cross-matching ID
TTD Drug ID
DMUWO6D

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sucralfate DMP9HBO Acne vulgaris ED80 Approved [2]
Squalamine DM3PS2E Solid tumour/cancer 2A00-2F9Z Phase 3 [3]
DVC1-0101 DMUGBQK Arteriosclerosis BD40 Phase 2 [4]
Bemarituzumab DMWNYIE Gastric adenocarcinoma 2B72 Phase 2 [5]
FPA144 DM1EBRK Bladder cancer 2C94 Phase 1 [6]
TGP-580 DMYN6G0 Neurodegenerative disorder 8A20-8A23 Discontinued in Phase 2 [7]
RG-8803 DMI0CYV Diabetic retinopathy 9B71.0 Terminated [8]
2-Sulfhydryl-Ethanol DMJBO3D Discovery agent N.A. Investigative [9]
N,O6-Disulfo-Glucosamine DMYCV7U Discovery agent N.A. Investigative [9]
1,4-Dideoxy-O2-Sulfo-Glucuronic Acid DM9KUQZ Discovery agent N.A. Investigative [9]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Brolucizumab DMW8QNG Wet age-related macular degeneration 9B78.3Z Approved [10]
Squalamine DM3PS2E Solid tumour/cancer 2A00-2F9Z Phase 3 [3]
PF-06439535 DMVHZDP Non-small-cell lung cancer 2C25.Y Phase 3 [11]
M710 DM1PRT6 Diabetic macular edema 9B71.02 Phase 3 [12]
FKB238 DM6R2XF Non-small-cell lung cancer 2C25.Y Phase 3 [13]
KSI-301 DMM2LTC Diabetic macular edema 9B71.02 Phase 3 [14]
TRS003 DMM1VOH Colorectal cancer 2B91.Z Phase 3 [15]
MYL-1402O DMXN2PP Non-small-cell lung cancer 2C25 Phase 3 [16]
SB15 DMTOS6C Neovascular age-related macular degeneration 9B78.3Z Phase 3 [17]
Dilpacimab DMCATH2 Solid tumour/cancer 2A00-2F9Z Phase 2 [18]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fibroblast growth factor-2 (FGF2) TTGKIED FGF2_HUMAN Inhibitor [1]
Vascular endothelial growth factor (VEGF) TT9HKJA VEGFA_HUMAN; VEGFB_HUMAN; VEGFC_HUMAN; VEGFD_HUMAN Inhibitor [1]

References

1 Emerging therapies for multiple myeloma. Expert Opin Emerg Drugs. 2009 Mar;14(1):99-127.
2 Assessment of sucralfate coating by sequential scintigraphic imaging in radiation-induced esophageal lesions. Gastrointest Endosc. 1995 Feb;41(2):109-14.
3 Clinical pipeline report, company report or official report of Ohr Pharmaceutical.
4 DVC1-0101 to treat peripheral arterial disease: a Phase I/IIa open-label dose-escalation clinical trial. Mol Ther. 2013 Mar;21(3):707-14.
5 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
6 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
7 Expression of fibroblast growth factor-2 transcripts in the healing of acetic acid-induced gastric ulcers. APMIS. 1999 Aug;107(8):767-72.
8 US patent application no. 2010,0278,784, Methods and compositions for treating skin conditions.
9 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
10 Brolucizumab: First Approval. Drugs. 2019 Dec;79(18):1997-2000.
11 National Cancer Institute Drug Dictionary (drug id 43234).
12 ClinicalTrials.gov (NCT03610646) Comparative Study to Evaluate the Efficacy and Safety of MYL-1701P and Eylea in Subjects With Diabetic Macular Edema. U.S. National Institutes of Health.
13 Clinical pipeline report, company report or official report of Fujifilm.
14 Clinical pipeline report, company report or official report of Kodiak Sciences.
15 Prevalence of porcine cysticercosis in Vellore, South India. Trans R Soc Trop Med Hyg. 2013 Jan;107(1):62-4.
16 MYL-1402O: A Bevacizumab Biosimilar. Target Oncol. 2022 Jan;17(1):85-88.
17 Efficacy and Safety of the Aflibercept Biosimilar SB15 in Neovascular Age-Related Macular Degeneration: A Phase 3 Randomized Clinical Trial. JAMA Ophthalmol. 2023 Jul 1;141(7):668-676.
18 Apoptogenic activity of 2alpha,3alpha-dihydroxyurs-12-ene-28-oic acid from Prunella vulgaris var. lilacina is mediated via mitochondria-dependent activation of caspase cascade regulated by Bcl-2 in human acute leukemia Jurkat T cells. J Ethnopharmacol. 2011 Jun 1;135(3):626-35.