Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMV0MHI)

Drug Name

EP-7041 Drug Info

Synonyms

QPVLDUCHRPJGCJ-QBIMZIAESA-N; SCHEMBL16998942

Indication

Disease Entry	ICD 11	Status	REF
Thrombosis	DB61-GB90	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Coagulation factor XI (F11)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
A186	DMHJ0EB	Clotting disorder	3B4Z	IND submitted	[2]
Asundexian	DMLZMU2	Ischemic stroke	8B11.5Z	Phase 3	[3]
Abelacimab	DM09YTN	Atrial fibrillation	BC81.3	Phase 2	[4]
MK-2060	DM79A32	Thrombosis	DB61-GB90	Phase 2	[5]
AB023	DMBG9HI	End-stage renal disease	GB61.5	Phase 1	[6]
A336	DMVQG8G	Clotting disorder	3B4Z	Phase 1	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	Clinical pipeline report, company report or official report of Klus Pharma
3	Pharmacological profile of asundexian, a novel, orally bioavailable inhibitor of factor XIa. J Thromb Haemost. 2022 Jun;20(6):1400-1411.
4	Pharmacokinetics and pharmacodynamics of Abelacimab (MAA868), a novel dual inhibitor of Factor XI and Factor XIa. J Thromb Haemost. 2022 Feb;20(2):307-315.
5	Clinical pipeline report, company report or official report of MSD
6	Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial. Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):799-809.