Details of the Drug

General Information of Drug (ID: DMBG9HI)

Drug Name
AB023
Indication
Disease Entry ICD 11 Status REF
End-stage renal disease GB61.5 Phase 1 [1]
Drug Type
Antibody
Cross-matching ID
PubChem CID
6474366
TTD ID
D4P8YO

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor XI (F11) TTJCPUT FA11_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03097341) Safety and Tolerability Study of Xisomab 3G3 in Healthy Adult Subjects. U.S. National Institutes of Health.
2 Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial. Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):799-809.