General Information of Drug (ID: DMV7ZU0)

Drug Name
GS-6624 Drug Info
Indication
Disease Entry ICD 11 Status REF
Colorectal cancer 2B91.Z Phase 2 [1]
Cross-matching ID
PubChem CID
17750227
TTD Drug ID
DMV7ZU0

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Preclinical Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-aminopropionitrile DMSJ2I6 Cardiac arrest MC82 Preclinical [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Lysyl oxidase homolog 2 (LOXL2) TTFSUHX LOXL2_HUMAN Not Available [2]

References

1 ClinicalTrials.gov (NCT01769196) A Phase 2 Study to See if Simtuzumab (GS-6624) is Safe and Works in Idiopathic Pulmonary Fibrosis (IPF). U.S. National Institutes of Health.
2 National Cancer Institute Drug Dictionary (drug id 681814).
3 Wnt signaling and Loxl2 promote aggressive osteosarcoma. Cell Res. 2020 Oct;30(10):885-901.