Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMWZXF7)

Drug Name
ORG-33628 Drug Info
Synonyms 11beta-(4-Acetylphenyl)-3'-methylenespiro[estra-4,9-dien-17(R),2'-tetrahydrofuran]-3-one
Indication
Disease Entry ICD 11 Status REF
Contraception QA21 Discontinued in Phase 2 [1]
Cross-matching ID
PubChem CID
9846209
CAS Number
CAS 155768-17-5
TTD Drug ID
DMWZXF7

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Progesterone (PG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
BAY 86-5044 DMRZLU4 Breast cancer 2C60-2C65 Phase 2 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Progesterone (PG) TTHL6YX NOUNIPROTAC Modulator [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018847)
2 ORG 33628 and ORG 31710 to control vaginal bleeding in progestin-only contraceptive regimens. Semin Reprod Med. 2005 Feb;23(1):101-11.
3 Randomized phase II study of lonaprisan as second-line therapy for progesterone receptor-positive breast cancer. Ann Oncol. 2013 Oct;24(10):2543-8.