Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMX1TIU)

Drug Name
2-[2-(3,5-Dimethoxy-phenyl)-vinyl]-thiophene Drug Info
Synonyms
CHEMBL42428; 2-[2-(3,5-Dimethoxy-phenyl)-vinyl]-thiophene; SCHEMBL7042974; SCHEMBL7042968; ZINC13471769; BDBM50108048; AKOS015967551; (E)-2-(3,5-dimethoxystyryl)thiophene; 2-[(E)-3,5-Dimethoxystyryl]thiophene
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
9834747
TTD Drug ID
DMX1TIU

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Cytochrome P450 1B1 (CYP1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PINOCEMBRIN DM96VWD N. A. N. A. Phase 2 [2]
NARINGENIN DMHAZLM N. A. N. A. Phase 1 [2]
Chrysin DM7V2LG Discovery agent N.A. Investigative [2]
APIGENIN DMI3491 Discovery agent N.A. Investigative [2]
KAEMPFEROL DMHEMUB Discovery agent N.A. Investigative [2]
ISORHAMNETIN DMQ4Z6E Discovery agent N.A. Investigative [2]
ACACETIN DMQOB0X Discovery agent N.A. Investigative [2]
TRISMETHOXYRESVERATROL DM6USPC Discovery agent N.A. Investigative [1]
Galangin DM5TQ2O Discovery agent N.A. Investigative [2]
CHRYSOERIOL DM96ECL Discovery agent N.A. Investigative [2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
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Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cytochrome P450 1B1 (CYP1B1) TTI84H7 CP1B1_HUMAN Inhibitor [1]

References

1 Design, synthesis, and discovery of novel trans-stilbene analogues as potent and selective human cytochrome P450 1B1 inhibitors. J Med Chem. 2002 Jan 3;45(1):160-4.
2 Selective inhibition of methoxyflavonoids on human CYP1B1 activity. Bioorg Med Chem. 2010 Sep 1;18(17):6310-5.